The 3 Best Allergists in Phoenix, AZ

Board-certified allergy & asthma specialists practicing in Scottsdale.

If over-the-counter antihistamines stopped working, or your symptoms run for months instead of weeks, a board-certified allergist-immunologist can test what you actually react to and treat the cause. That includes immunotherapy, which lowers your sensitivity over three to five years. Our editors picked the 3 specialists below from the wider Arizona list based on board certification, hospital and academic affiliations, and peer recognition.

Allergists in Phoenix at a Glance

Specialists listed:
3, all board-certified in Allergy & Immunology
Areas covered:
Scottsdale
Practices:
Mayo Clinic Arizona
Local pollen season:
The Valley runs its own calendar. Mulberry and olive peak in February and March, which is why Phoenix has banned planting both since 1986, and irrigated Bermuda grass keeps grass pollen going most of the year. Ragweed and careless weed follow the summer monsoon in September and October.

Compare Phoenix Allergists

AllergistPracticeLocationKnown for
Matthew A. Rank, MDMayo Clinic Arizona / Phoenix Children's HospitalScottsdale, AZAsthma, Chronic sinusitis, Severe asthma biologics
John C. Lewis, MDMayo Clinic ArizonaScottsdale, AZImmunodeficiency, Eosinophilic esophagitis, Asthma
Alexei Gonzalez-Estrada, MDMayo Clinic ArizonaScottsdale, AZHereditary angioedema, Anaphylaxis, Drug hypersensitivity
  1. 1

    Matthew A. Rank, MD

    Mayo Clinic Arizona / Phoenix Children's Hospital

    Scottsdale, AZ

    Board-certified in Allergy & ImmunologyBoard-certified in Internal MedicineBoard-certified in PediatricsMD, University of Wisconsin School of Medicine & Public HealthFellowship in Allergy & Immunology, Mayo ClinicAssociate Professor of Medicine and Otolaryngology, Mayo Clinic Arizona

    Dr. Rank is the Program Director of the Mayo Clinic Allergy and Immunology Fellowship in Arizona and co-director of both the Multidisciplinary Clinic for Challenging Sinus Disease and the Severe Asthma Clinic at Phoenix Children's Hospital. He also holds an academic appointment at the University of Arizona College of Medicine – Phoenix.

    Areas of focus: Asthma · Chronic sinusitis · Severe asthma biologics · Pediatric allergy

    Visit practice website →
  2. 2

    John C. Lewis, MD

    Mayo Clinic Arizona

    Scottsdale, AZ

    Board-certified in Allergy & ImmunologyBoard-certified in Internal MedicineMD, Loyola University Chicago Stritch School of MedicineFellowship in Allergy & Immunology, Mayo Clinic Rochester

    Dr. Lewis has been practicing at Mayo Clinic Arizona for over 20 years following his fellowship training at Mayo Clinic in Rochester. He specializes in complex immunodeficiency syndromes including hypogammaglobulinemia and eosinophilic esophagitis.

    Areas of focus: Immunodeficiency · Eosinophilic esophagitis · Asthma · Autoimmune disease · Hypogammaglobulinemia

    Visit practice website →
  3. 3

    Alexei Gonzalez-Estrada, MD

    Mayo Clinic Arizona

    Scottsdale, AZ

    Board-certified in Allergy & ImmunologyMD, Universidad Anahuac School of MedicineResidency in Internal Medicine, Cleveland Clinic FoundationFellowship in Allergy & Immunology, Cleveland Clinic Foundation

    Dr. Gonzalez-Estrada is a faculty allergist-immunologist at Mayo Clinic Scottsdale with specialized expertise in hereditary angioedema, anaphylaxis, and drug hypersensitivity. He trained at the Cleveland Clinic Foundation and sees patients across the full spectrum of allergic and immunologic conditions.

    Areas of focus: Hereditary angioedema · Anaphylaxis · Drug hypersensitivity · Food allergy · Allergen immunotherapy

    Visit practice website →

Allergy Season in Phoenix

The Valley runs its own calendar. Mulberry and olive peak in February and March, which is why Phoenix has banned planting both since 1986, and irrigated Bermuda grass keeps grass pollen going most of the year. Ragweed and careless weed follow the summer monsoon in September and October.

Bring dates to your appointment. An allergist can narrow the list of suspects much faster when you can say “this started the second week of April” and match it against what was actually in the air.

Source: Phoenix City Code Section 39-9: Airborne Pollens. phoenix.municipal.codes

How We Picked These Phoenix Allergists

Our editorial team reviewed allergy and immunology specialists practicing across the Phoenix metro and selected these 3 on:

  • Board certification in Allergy & Immunology (ABAI)
  • Hospital and academic affiliations with respected medical centers
  • Peer recognition, including Top Doctor awards and professional society roles
  • Practice reputation and years treating allergy and asthma patients
  • Coverage across the metro, so the list is not all one hospital system

These listings are editorial picks, not paid placements or medical endorsements, and we have no financial relationship with any provider listed. Availability, insurance participation, and credentials change. Verify directly with the practice before booking. This page is for informational purposes and is not medical advice.

Frequently Asked Questions

Who are the best allergists in Phoenix?

Our editors picked 3 board-certified allergist-immunologists practicing in the Phoenix metro: Matthew A. Rank, MD at Mayo Clinic Arizona / Phoenix Children's Hospital in Scottsdale; John C. Lewis, MD at Mayo Clinic Arizona in Scottsdale; Alexei Gonzalez-Estrada, MD at Mayo Clinic Arizona in Scottsdale. All are board-certified in Allergy & Immunology.

When is allergy season in Phoenix?

The Valley runs its own calendar. Mulberry and olive peak in February and March, which is why Phoenix has banned planting both since 1986, and irrigated Bermuda grass keeps grass pollen going most of the year. Ragweed and careless weed follow the summer monsoon in September and October.

See today's pollen count in Phoenix →

Do I need a referral to see an allergist in Phoenix?

That depends on your insurance plan, not your city. Most PPO plans let you book straight with an allergist. HMO plans usually want a referral from your primary care doctor first. Call the practice or your insurer before you book.

How much does an allergist visit cost in Phoenix?

A first visit with a specialist typically runs $150 to $300 without insurance, and skin testing for a panel of environmental allergens usually adds $200 to $1,000 depending on how many allergens are tested. With insurance you pay your specialist copay, though testing is often billed separately. Ask the office for a cost estimate and their billing codes when you book.

What should I bring to my first allergist appointment?

Bring a list of your symptoms and the dates they flared, every medication you take including over-the-counter ones, your insurance card, and any past test results. Stop antihistamines 5 to 7 days before skin testing, since they can blunt the results. Confirm the exact timing with the office.

Check Phoenix pollen levels to match your flare dates →

Are these Phoenix allergists accepting new patients?

That changes month to month, so call the practice to check. These are editorial picks, not paid placements, and we have no financial relationship with any provider listed. Verify current credentials, availability, and insurance participation directly with the office before you book.

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Before You Call

Start a symptom log this week. Note the day, what you felt, and what the pollen count was. Two or three weeks of that turns a vague “my allergies are bad” into something an allergist can work from.

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