The 5 Best Allergists in Arizona
Board-certified allergy & asthma specialists in Scottsdale, Tucson.
If over-the-counter antihistamines aren't cutting it anymore, a board-certified allergist-immunologist can pinpoint exactly what you're reacting to and build a treatment plan — including immunotherapy that can reduce your sensitivity for good. Our editors researched allergists across Arizona and curated the five standouts below based on board certification, affiliations, peer recognition, and patient reputation. Before your visit, check today's pollen levels in Arizona so you can tell your doctor what was in the air when your symptoms flared.
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Matthew A. Rank, MD
Mayo Clinic Arizona / Phoenix Children's Hospital
Scottsdale, AZ
Board-certified in Allergy & ImmunologyBoard-certified in Internal MedicineBoard-certified in PediatricsMD, University of Wisconsin School of Medicine & Public HealthFellowship in Allergy & Immunology, Mayo ClinicAssociate Professor of Medicine and Otolaryngology, Mayo Clinic ArizonaDr. Rank is the Program Director of the Mayo Clinic Allergy and Immunology Fellowship in Arizona and co-director of both the Multidisciplinary Clinic for Challenging Sinus Disease and the Severe Asthma Clinic at Phoenix Children's Hospital. He also holds an academic appointment at the University of Arizona College of Medicine – Phoenix.
Areas of focus: Asthma · Chronic sinusitis · Severe asthma biologics · Pediatric allergy
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John C. Lewis, MD
Mayo Clinic Arizona
Scottsdale, AZ
Board-certified in Allergy & ImmunologyBoard-certified in Internal MedicineMD, Loyola University Chicago Stritch School of MedicineFellowship in Allergy & Immunology, Mayo Clinic RochesterDr. Lewis has been practicing at Mayo Clinic Arizona for over 20 years following his fellowship training at Mayo Clinic in Rochester. He specializes in complex immunodeficiency syndromes including hypogammaglobulinemia and eosinophilic esophagitis.
Areas of focus: Immunodeficiency · Eosinophilic esophagitis · Asthma · Autoimmune disease · Hypogammaglobulinemia
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Alexei Gonzalez-Estrada, MD
Mayo Clinic Arizona
Scottsdale, AZ
Board-certified in Allergy & ImmunologyMD, Universidad Anahuac School of MedicineResidency in Internal Medicine, Cleveland Clinic FoundationFellowship in Allergy & Immunology, Cleveland Clinic FoundationDr. Gonzalez-Estrada is a faculty allergist-immunologist at Mayo Clinic Scottsdale with specialized expertise in hereditary angioedema, anaphylaxis, and drug hypersensitivity. He trained at the Cleveland Clinic Foundation and sees patients across the full spectrum of allergic and immunologic conditions.
Areas of focus: Hereditary angioedema · Anaphylaxis · Drug hypersensitivity · Food allergy · Allergen immunotherapy
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George J. Makol, MD
Aspire Allergy & Sinus
Tucson, AZ
Board-certified in Allergy & ImmunologyBoard-certified in Internal MedicineMD, University of Miami School of MedicineFellowship in Allergy & Clinical Immunology, University of Arizona Health Sciences CenterDr. Makol has practiced allergy and immunology in Tucson for several decades and has twice served as president of both the Arizona Allergy & Asthma Society and the Tucson Allergy Society. He completed his allergy fellowship at the University of Arizona Health Sciences Center and treats patients of all ages.
Areas of focus: Allergic rhinitis · Asthma · Immunotherapy · Adult and pediatric allergy
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Puneet Shroff, MD
Banner University Medicine / University of Arizona College of Medicine – Tucson
Tucson, AZ
Board-certified in Allergy & ImmunologyBoard-certified in Internal MedicineBoard-certified in RheumatologyMD, University of Illinois College of Medicine at ChicagoResidency in Internal Medicine, Washington University in St. LouisFellowship in Allergy & Immunology and Rheumatology, Baylor College of MedicineFaculty, University of Arizona Division of Pulmonary, Allergy, Critical Care & Sleep MedicineDr. Shroff holds a rare triple board certification in Allergy & Immunology, Internal Medicine, and Rheumatology, and joined the University of Arizona faculty in 2018 after building a private practice in Houston. He has trained at Washington University, Baylor College of Medicine, and the University of Oxford.
Areas of focus: Allergy & immunotherapy · Rheumatologic immunologic overlap · Asthma · Integrative medicine
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How we chose the best allergists in Arizona
Our editorial team researched allergy and immunology specialists practicing across Arizona and selected these five based on:
- Board certification in Allergy & Immunology (ABAI)
- Hospital and academic affiliations with respected medical centers
- Peer recognition, including Top Doctor awards and professional society roles
- Practice reputation and years of experience treating allergy and asthma patients
- Geographic spread across Arizona's major metro areas
These listings are editorial picks, not paid placements or medical endorsements, and we have no financial relationship with any provider listed. Physician availability, insurance participation, and credentials change — always verify directly with the practice before booking. This page is for informational purposes and is not medical advice.
Frequently asked questions
How do I find a good allergist in Arizona?
Look for board certification in Allergy & Immunology, hospital or academic affiliations, and an established practice. Every allergist on this list was vetted against those criteria.
Do I need a referral?
It depends on your insurance plan, not the state. Most PPO plans let you book directly; HMO plans usually require a referral from your primary care physician.
What should I bring to my first appointment?
A list of your symptoms and when they occur, your current medications, your insurance card, and any relevant medical records. A symptom diary matched against local pollen counts is especially useful for diagnosing seasonal allergies.
Track Arizona pollen before your visit
Allergists can diagnose you faster when you know which days your symptoms flared and what was in the air. MyPollenPal tracks daily tree, grass, and weed pollen levels for cities across Arizona.